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Good morning. The obesity data keeps coming this week. We’ll get straight into it.
The need-to-know this morning
- Rezolute said its experimental drug failed to reduce episodes of low blood sugar in patients with congenital hyperinsulinism, missing the efficacy goal of a Phase 3 trial.
- AC Immune said its immunotherapy showed the potential to slow the progression of Parkinson’s disease, based on preliminary results from a mid-stage study.
- Rhythm Pharma announced preliminary study data showing its drug could reduce hunger cravings and lower the BMI of people with Prader-Willi Syndrome.
- Geron announced a corporate restructuring, including a one-third reduction in its workforce.
Lilly’s triple-G drug leads to major weight loss, but with many discontinuations
Eli Lilly’s next-generation obesity drug led to what appears to be the most weight loss seen so far in a late-stage trial, but rates of side effects were high and many participants discontinued the treatment, including people who felt they were losing too much weight.
Continue to STAT+ to read the full story…
STAT Pharma: The science and business of new drug development






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